Hassan Wajid-Muscular Dystrophy-(Pakistan)

Name: Hassan Wajid
Sex: Male
Nationality: Pakistani
Age: 13
Diagnosis: Muscular Dystrophy (MD)
Date of Admission: May 11, 2016
Treatment hospital/period: Wu Medical Center/20days

Before treatment:
In 2005, he was found higher level of CK, but his motor function was normal. His older sister showed the same test result and had motor disorders. In 2007, he did gene test and diagnosed with muscular dystrophy. In 2010, he began to have muscular weakness, muscular atrophy, his condition got worse, his knee joints and ankle joints were atrophied. His condition got worse 1 year ago, he was not able to stand, turn over or sit up, he needed wheelchair to move around.
At present, he is able to keep in sitting position, he is not able to take care of himself. His spirit is good. He sleeps and eats well. His urination and defecation are normal.

Admission PE:
Bp: 109/67mmHg, Hr: 91/min. Temperature: 36.5 degrees. His skin and mucous membranes were complete, with no yellow stains or petechia on skin and mucous. The respiration of him was clear, there was no dry or moist rales. The rhythm of his heartbeat was normal with no obvious murmur in the valves. His abdomen was soft and flat with no pressing pain or rebound tenderness. The liver and spleen were normal. He had shoulder girdle, pelvic girdle and four limbs’ muscular atrophy. His ankle joints and knee joints were slightly contractural. There was no edema on both lower limbs. Blood routine: CK 2756 IU/L, AST 62IU/L.

Nervous System Examination:
Hassan Wajid was alert and his spirit was good. His memory, calculation ability, comprehension and orientation were normal. Both pupils were equal in size and round, the diameter was 3 mms, both eyes had sensitive response to light stimuli. Both eyeballs could move freely. He had no nystagmus. The nasolabial fold and forehead wrinkle pattern were symmetrical. He was able to close his eyes strongly. The tongue was centered in the oral cavity. He didn’t have teeth deflection, when he did check blowing, there was no leak of gas. He was able to raise his soft palates powerful. He turned over his head and shrugged his shoulders weakly. The abductor muscle power of left upper arm was at level 2+, adductor muscle power was at level 2, the flexor muscle power of left forearm was at level 2, extensor muscle power was at level 3, the muscle power of extend and flex his wrist was at level 4. The abductor muscle power of right upper arm was at level 2+, adductor muscle power was at level 2, the flexor muscle power of right forearm was at level 2, extensor muscle power was at level 3+, the muscle power of mextend and flex his wrist was at level 4. The grip of both hands was at level 4. The muscle power of bend, extend and abduct hips were at level 1, the muscle power of adduct was at level 2. The flexor muscle power of knees was at level 3-, the extensor muscle power was at level 2+. The dorsiflexion and planter flexion muscle power of ankle were at level 2. The muscle tension of four limbs was lower than normal. The tendon reflex was abnormal, abdominal reflexes were weaker. Bilateral pathological sign was negative. His deep sensation, superficial sensation and epicritic sensation were normal. He was not able to do the finger to nose test, he did the finger to finger test and rapid rotation test slowly. He was not able to do the heel-knee-tibia test. The meningeal irritation sign was negative.

Treatment:
He was diagnosed with duscular dystrophy, he received 4 neural stem cell injections and 4 mesenchymal stem cell injections to active the stem cells in his body, repair the damaged cells, protect his organs function, regular his immune function, improve his blood circulation, nourish neurons and muscle cells, repaired damaged muscle cells. We also gave him daily physical rehabilitation.

Post-treatment:
After 20 days of treatment, his exercise tolerance was better, he had better energy and spirit. When he did rehabilitation training, he felt not so tired.
The muscle power of both upper limbs was higher, he was able to touch his head with lift upper arm. His upper limbs and fingers were more flexible, his grip was better. The muscle power of his back was higher than before, his sitting position was better. The muscle power of hips and lower limbs was half to one level higher, his lower limbs were more flexible. The abductor muscle power of left upper arm was at level 2+, adductor muscle power was at level 2+, the flexor muscle power of left forearm was at level 2+, extensor muscle power was at level 3+, the muscle power of extend and flex his wrist was at level 4. The abductor muscle power of right upper arm was at level 2+, adductor muscle power was at level 2+, the flexor muscle power of right forearm was at level 2+, extensor muscle power was at level 3+, the muscle power of extend and flex his wrist was at level 4. The grip of both hands was at level 4+. The deformity of his knees resulting from a contracture was better. CK level was lower than before, CK948 IU/L, AST 54 IU/L.

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