Metodi Mitev-Myelopathy-(Macedonia)

Name: Metodi Mitev
Sex: Male
Nationality: Macedonian
Diagnosis: Myelopathy
Discharge Date: 2018/03/28

Before treatment:
The patient felt pain in his right leg 3 years ago and as time went by he also felt pain in his back and chest. The muscle power in his right leg decreased and he was diagnosed with hereditary paralysis by a local hospital. His condition got worse and worse with the muscle power in his left leg decreasing and the sensation function of his legs decreased. He was unable to walk in July 2017. In recent days he has had temporary problems with language. At present he uses a wheelchair, he can turn over and sit up with the help of arms, but he can’t stand or walk. He is hospitalized with the diagnosis of Myelopathy.
His spirit, diet and sleep, urination and defecation functions are all normal.

Admission PE:
Bp: 136/85mmHg, Hr: 85/min, breathing rate: 20/min. height 170cm, weight 140Kg. Good nutrition status but overweight. There is no injury or bleeding spots of his skin and mucosa, no congestion of the throat and no tonsil swelling. Chest development is normal, the lungs breathing sounds were clear with no rales, The heart beat was powerful with regular cardiac rhythm and no murmur in the valve areas. The abdomen was soft and bulging with no masses or tenderness. His liver and spleen were normal, shifting dullness was negative, spinal column was normal and there was no edema of the legs.

Nervous System Examination:
Patient was alert, had clear speech and his mental status was fine. His memory, calculation and orientation abilities are normal. Both pupils were equal in size and round, diameter of 3.0 mm, react well to light with no nystagmus. The bilateral forehead wrinkle and nasolabial groove are symmetrical, he can extend his tongue out as normal, showing teeth was normal, he could move his head and shrug as normal. The muscle power of the arms was 4 degrees, of the legs it was 0. The 4 limbs muscle tone was normal,  tendon reflex of the arms was normal. The leg patellar tendon reflex and  Achilles tendon reflex could not be induced by examination. The abdominal reflex could not be induced by examination. Sensory system examination: superficial sensory: the arms vibration sense and position sensory were normal, the vibration sensory disappeared below the hip. Bilateral Hoffmann sign and Rossilimo sign were negative. The palm-jaw reflex of both sides and the bilateral Babinski signs were negative. The Ankle clonus was negative, the coordinate movement examination was normal. He could not perform the heel-knee-tibia test because of weakness.

After the admission, he received 3 nerve regeneration treatments (neural stem cells and mesenchymal stem cells) to repair damaged spinal cord nerves, replace dead nerves, nourish nerves, improve blood circulation, improve the nutrition supply. This was combined with rehabilitation training.

After 15 days treatment his arm muscle power increased, his hands grip force improved, the muscles of his right leg presented, contracted and the muscle power increased 20%. His sensory results got better with the sensation function of the spine improved by two levels.

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